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2-Chloroacetophenone alpha-氯乙酰苯

规格: 98%

CAS: 532-27-4

产品编号: H79011

MDL: MFCD00000933

品牌: INFI

Chemical Name	Phenacyl Chloride
MDL Number	MFCD00000933
Synonym	氯代乙酰苯 Α-氯代苯乙酮 2-CHLORO-1-PHENYLETHANONE PHENACYL CHLORIDE 2-氯乙酰苯氯苯乙酮 A-CHLOROACETOPHENONE Ethanone, 2-chloro-1-phenyl- CN Chemical mace 1-Chloroacetophenone ω-氯代苯乙酮 Chloromethyl phenyl ketone 2-chloro-1-phenyl-ethanon α-氯代苯乙酮 Chloromethyl phenylketone 2-Chloro-1-oxoethyl)benzene "teargas"[qr] alpha-氯乙酰苯 BETA-CHLOROACETOPHENONE ALPHA-氯代丙酰氯 2-chloro-acetophenon ALPHA-氯苯乙酮 PHENACYLCHLORID Α-氯苯乙酮 Acetophenone, 2-chloro- 2-chloro-1-phenylethanone[qr] 苯基氯甲基甲酮 Phenacyl chloride NCI-C55107 Α-氯乙酰苯氯化苯乙酮 2-Chloro-1-phenylethanone ALPHA-CHLOROACETOPHENONE OMEGA-CHLOROACETOPHENONE W-CHLOROACETOPHENONE omega-Chloroacetophenone alpha-氯代苯乙酮 1-chloroacetophenone[qr] 2-Chloroacetophenone Phenylchloromethylketone 2-氯苯乙酮,99% alpha-Chloroacetophenone 2-CHLOROACETOPHENONE a-phenacyl chloride 苯酰甲基氯 2-氯苯乙酮氯乙酰苯 Mace (lacrimator) acetophenone,2-chloro-
EC Number	208-531-1
CAS Number	532-27-4
Merck Number	14,2115
Beilstein Registry Number	0507950
PubChem Substance ID	24892454
Alfabeta Name	CHLOROACETOPHENONE 2-
Chemical Name Translation	苯甲酰甲基氯
Wiswesser Line Notation	G1VR
LabNetwork Molecule ID	LN00182275

GHS Symbol

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 mg/m3/6H/2Y-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Endocrine - tumors
   Skin and Appendages - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-379,1990

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2400 mg/kg/27W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   7,482,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   40,75,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 139 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD837-111

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 118 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
   Lungs, Thorax, or Respiration - other changes
   Skin and Appendages - hair
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   40,75,1978

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 93 mg/m3/3M
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Sense Organs and Special Senses (Eye) - conjunctive irritation
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AIHAAP American Industrial H

TYPE OF TEST            : LD50 - Lethal d

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 3 mg/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-379,1990

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 10 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 368,59,1996

RTECS	AM6300000
Safety Statements
S9 Keep container in a well-ventilated place 保持容器在通风良好的场所； S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护； S20 When using do not eat or drink 使用时，不得进食，饮水； S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）； S22 Do not breathe dust 不要吸入粉尘； S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
Packing Group	II
UN Number	UN1697 UN 1693 6.1/PG 2
Risk Statements
R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性 R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒 R41 Risk of serious damage to eyes 有严重损伤眼睛的危险 R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性 R25 Toxic if swallowed 吞咽有毒 R42/43 R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
Storage condition	Moisture Sensitive
WGK Germany	3
Hazard statements
H315 Causes skin irritation 会刺激皮肤 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难 H335 May cause respiratory irritation 可能导致呼吸道刺激 H300 Fatal if swallowed 吞食致命 H318 Causes serious eye damage 严重伤害眼睛 H311+H331
Personal Protective Equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Precautionary statements
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P301+P310 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P305+P351+P338 P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
Signal word	Danger
Warnings	危化品目录(2015) IRRITANT
Hazard Codes	T
Hazard Class	6.1
Restrict	危险品

532-27-4 H79011 2-Chloroacetophenone
alpha-氯乙酰苯

化学属性

Mol. Formula	C8H7ClO
Mol. Weight	154.60
Density	1.324
Flash Point	118°(244°F)
TSCA	Yes
Boiling Point	243-244°
Melting Point	54-56 °C(lit.)
Solubility	insoluble. <0.1 g/100 mL at 19 °C
Refractive index	1.5438

*以上化合物性质及应用等信息仅供参考

手性催化剂及配体

合成砌块

医药中间体

2-Chloroacetophenone alpha-氯乙酰苯

规格: 98%

化学属性

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