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1,4-Naphthoquinone 1,4-萘醌

规格: 95%

CAS: 130-15-4

产品编号: H21334

MDL: MFCD00001676

品牌: INFI

Chemical Name	1,4-Naphthoquinone
Synonym	1,4-Naphthoquinone {LY} 1,4-Naphthoquinone {} {LY} 1,4-Naphthoquinone {} {} {LY} 1,4-Naphthoquinone {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL Number	MFCD00001676
Beilstein Registry Number	7,724
CAS Number	130-15-4
EC Number	204-977-6
PubChem Substance ID	8530
Reaxys-RN	878524
Merck Number	14,6395
Chemical Name Translation	1,4-二萘醌(1,4-萘二醌)
Wiswesser Line Notation	L66 BV EVJ
LabNetwork Molecule ID	LN00196373
InChI	InChI=1S/C10H6O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H
Canonical SMILES	O=C1C=CC(C2=C1C=CC=C2)=O

GHS Symbol

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg/29W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appendages - tumors
REFERENCE :
   PIATA8 Proceedings of the Imperial Academy of Tokyo.  (Tokyo, Japan) V.1-21,
   1912-45.  For publisher information, see PJACAW. Volume(issue)/page/year:
   16,309,1940

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 71,210,1941

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 202 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 16(5),52,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5500 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,570,1983

TYPE OF TEST

{ha

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 393,23,1997

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   57,466,1955

RTECS	QL7175000
WGK Germany	3
Hazard Codes	6.1 T+,N T+,N,T
Hazard statements
H301+H311 H315 Causes skin irritation 会刺激皮肤 H330 Fatal if inhaled 吸入致命 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难 H301 Toxic if swallowed 吞食有毒 H335 May cause respiratory irritation 可能导致呼吸道刺激 H400 Verytoxictoaquaticlife 对水生生物毒性非常大。 H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Precautionary statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。 P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。 P273 Avoid release to the environment. 避免释放到环境中。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P284 Wear respiratory protection.? 佩戴呼吸保护装置。 P301+P310 P302+P350 P304+P340+P310 P305+P351+P338 P308+P313 P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。 P337+P313 P403+P233 P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word	Danger
UN Number	2811 UN 2811 6.1/PG 1
Safety Statements
S24 Avoid contact with skin 避免皮肤接触； S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护； S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）； S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
Risk Statements
R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒 R25 Toxic if swallowed 吞咽有毒 R26 Very toxic by inhalation 吸入极毒 R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性 R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应 R50 Very toxic to aquatic organisms 对水生生物极毒
Packing Group	I
Hazard Class	6.1
Storage condition	2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

用于有机合成，可制染料中间体蒽醌，农药杀菌剂、除草剂，用于合成橡胶，合成树脂的聚合调节剂等。

{uni_hamburg} Short: II/27B

{ALD} Merck: 14,6395

{uni_hamburg} Short: II/27C

{ALD} Merck: 14,6395

Beilstein:7,724

130-15-4 H21334 1,4-Naphthoquinone 1,4-萘醌

化学属性

Mol. Formula	C10H6O2
Mol. Weight	158.16
Melting Point	119 - 122 °C
Density	1.42
Flash Point	142°(288°F)
TSCA	Yes
Solubility	不溶
Appearance	黄色晶体。微溶于水。溶于乙醚、氯仿、苯、冰醋酸。
Boiling Point	243.22 °C at 760 mmHg

*以上化合物性质及应用等信息仅供参考

手性催化剂及配体

合成砌块

医药中间体

1,4-Naphthoquinone 1,4-萘醌

规格: 95%

化学属性

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