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4’-Hydroxypropiophenone 对羟基苯丙酮

规格: 97%

CAS: 70-70-2

产品编号: H11922

MDL: MFCD00002361

品牌: INFI

Chemical Name	p-Hydroxypropiophenone
CAS Number	70-70-2
Alfabeta Name	HYDROXYPROPIOPHENONE 4-'
MDL Number	MFCD00002361
Synonym	1-(4-Hydroxyphenyl)-1-propanone 4-hydroxypropiophenone 4-羟基苯丙酮 Ethyl 4-Hydroxyphenyl Ketone H-365 POP USAF EK-3302 p-Oxypropiophenone p-hydroxypropiophenone para-hydroxypropiophenone 对羟基苯丙酮
Beilstein Registry Number	907511
Reaxys-RN	907511
PubChem Substance ID	6271
Merck Number	7044
EC Number	200-743-2
Chemical Name Translation	对羟基苯丙酮
Wiswesser Line Notation	QR DV2
LabNetwork Molecule ID	LN00175127
InChI	InChI=1S/C9H10O2/c1-2-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

GHS Symbol

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,29,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 91 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 124,212,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1130 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 124,212,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 1600 mg/kg
SEX/DURATION            : female 15-30 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - eye/ear
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Effects on Newborn - stillbirth
REFERENCE :
   AOGNAX Archivio di Ostetricia e Ginecologia.  (C.C. Postale N 6/19773,
   Naples, Italy)  V.1-    1894-  Volume(issue)/page/year: 66,286,1961

Warnings	IRRITANT
RTECS	UH1925000
Signal word	Warning
Hazard statements
H315 Causes skin irritation 会刺激皮肤 H319 Causes serious eye irritation 严重刺激眼睛 H335 May cause respiratory irritation 可能导致呼吸道刺激
Precautionary statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P264+P265 P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P302+P352 P304+P340 P305+P351+P338 P305+P351+P338+P337+P313 P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。 P319 P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。 P332+P313 P332+P317 P337+P313 P337+P317 P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用 P362+P364 P403+P233 P405 Store locked up. 上锁保管。 P501 Dispose of contents/container to..… 处理内容物/容器.....
Safety Statements
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S36 Wear suitable protective clothing 穿戴适当的防护服； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护； S37 Wear suitable gloves 戴适当手套；
Risk Statements
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
WGK Germany	3
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi

{ALD} Merck: 14,7044

Beilstein:8,102

70-70-2 H11922 4’-Hydroxypropiophenone 对羟基苯丙酮

化学属性

Mol. Formula	C9H10O2
Mol. Weight	150
Melting Point	148-149
Flash Point	180°(356°F)
TSCA	Yes
Solubility	0.34 G/L (15 ºC)
Density	1.104

*以上化合物性质及应用等信息仅供参考

手性催化剂及配体

合成砌块

医药中间体

4’-Hydroxypropiophenone 对羟基苯丙酮

规格: 97%

化学属性

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